All products Antibodies Cathepsin D

Cathepsin D

Catalog Number：OM638929

  • Fig1: Western blot analysis of Cathepsin D on MCF-7 cell lysate using anti-Cathepsin D antibody at 1/1,000 dilution.

  • Fig2: ICC staining Cathepsin D in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig3: ICC staining Cathepsin D in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig4: ICC staining Cathepsin D in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig5: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Fig7: Flow cytometric analysis of HepG2 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

  • Fig8: Flow cytometric analysis of MCF-7 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Product Profile

Product Name Cathepsin D
Antibody Type Primary Antibodies
Product description 
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
Immunogen 
Peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200
Species Reactivity

HumanMouse
Concentration 1 mg/mL.

Target Information

Alternative Names
CatD antibody CATD_HUMAN antibody Cathepsin D antibody Cathepsin D heavy chain antibody CD antibody Ceroid lipofuscinosis neuronal 10 antibody CLN10 antibody CPSD antibody ctsd antibody Epididymis secretory sperm binding protein Li 130P antibody HEL S 130P antibody Lysosomal aspartyl peptidase antibody Lysosomal aspartyl protease antibody MGC2311 antibody
Molecular Weight(MW)

27 kDa

Cellular Localization Lysosome. Melanosome. Secreted, extracellular space.

Database Links

SwissProt ID P07339
P18242

Application

  • Application

    Fig1: Western blot analysis of Cathepsin D on MCF-7 cell lysate using anti-Cathepsin D antibody at 1/1,000 dilution.

  • Application

    Fig2: ICC staining Cathepsin D in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig3: ICC staining Cathepsin D in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig4: ICC staining Cathepsin D in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig5: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Application

    Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Application

    Fig7: Flow cytometric analysis of HepG2 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

  • Application

    Fig8: Flow cytometric analysis of MCF-7 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Positive Control MCF-7, Hela, HepG2, human liver tissue, human lung tissue.
Application Notes
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638929
  • Price: $336.00
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