All products Antibodies Cathepsin D

Cathepsin D

Catalog Number：OM638933

  • Fig1: Western blot analysis of Cathepsin D on different cell lysates using anti-Cathepsin D antibody at 1/1,000 dilution. Positive control: Lane 1: PC-12 Lane 2: MCF-7 Lane 3: NIH-3T3 Lane 4: Jurkat

  • Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Fig4: Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Fig5: Flow cytometric analysis of A549 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Product Profile

Product Name Cathepsin D
Antibody Type Primary Antibodies
Product description 
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
Immunogen 
Recombinant protein

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHCFC
WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity

HumanMouseRat
Concentration 1 mg/mL.

Target Information

Alternative Names
CatD antibody CATD_HUMAN antibody Cathepsin D antibody Cathepsin D heavy chain antibody CD antibody Ceroid lipofuscinosis neuronal 10 antibody CLN10 antibody CPSD antibody ctsd antibody Epididymis secretory sperm binding protein Li 130P antibody HEL S 130P antibody Lysosomal aspartyl peptidase antibody Lysosomal aspartyl protease antibody MGC2311 antibody
Molecular Weight(MW) 45/27 kDa
Cellular Localization Lysosome. Melanosome. Secreted, extracellular space.

Database Links

SwissProt ID P07339
P18242
P24268

Application

  • Application

    Fig1: Western blot analysis of Cathepsin D on different cell lysates using anti-Cathepsin D antibody at 1/1,000 dilution. Positive control: Lane 1: PC-12 Lane 2: MCF-7 Lane 3: NIH-3T3 Lane 4: Jurkat

  • Application

    Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Application

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Application

    Fig4: Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-Cathepsin D antibody. Counter stained with hematoxylin.

  • Application

    Fig5: Flow cytometric analysis of A549 cells with Cathepsin D antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Positive Control PC-12, MCF-7, NIH-3T3, Jurkat, rat liver tissue, human liver tissue, mouse brain tissue.
Application Notes
WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100

Additional Information

Form Liquid
Storage Instructions Store at +4℃after thawing. Aliquot store at -20℃or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638933
  • Price: $336.00
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  • Lead time: 4~6 Week

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