All products Antibodies Cox-1 Antibody (H-62) PE

Cox-1 Antibody (H-62) PE

Catalog Number：OM172823

  • Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of epidermal cells.

  • Western blot analysis of Cox-1 expression in NIH/3T3 whole cell lysate.

  • Western blot analysis of Cox-1 expression in U-937 whole cell lysate.

  • Intracellular FCM analysis of fixed and permeabilized NIH/3T3 cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Western blot analysis of Cox-1 expression in KNRK (A) and NIH/3T3 (B) whole cell lysates.

Product Profile

Product Name Cox-1 Antibody (H-62) PE
Antibody Type Primary Antibodies
Modification Notes Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs (NSAIDs).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFFCELISA
recommended for detection of Cox-1 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine and porcine:
Species Reactivity

HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified

Target Information

Alternative Names
epitope corresponding to amino acids 63-124 of Cox-1 of human origin
Tissue Specificity epitope corresponding to amino acids 63-124 of Cox-1 of human origin

Database Links

Entrez Gene 5742

Application

  • Application

    Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of epidermal cells.

  • Application

    Western blot analysis of Cox-1 expression in NIH/3T3 whole cell lysate.

  • Application

    Western blot analysis of Cox-1 expression in U-937 whole cell lysate.

  • Application

    Intracellular FCM analysis of fixed and permeabilized NIH/3T3 cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Application

    Western blot analysis of Cox-1 expression in KNRK (A) and NIH/3T3 (B) whole cell lysates.

Application Notes
recommended for detection of Cox-1 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine and porcine:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM172823
  • Price: $336.00
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  • Lead time: 4~6 Week

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