All products Antibodies JNK Antibody (FL) AC

JNK Antibody (FL) AC

Catalog Number：OM170849

  • Antibodies tested include p-JNK (89.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Antibodies tested include p-JNK (29.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Antibodies tested include p-JNK (14.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Antibodies tested include p-JNK (G-7): (A,B,C) and JNK (FL): (D,E,F).

  • Antibodies tested include p-JNK (Thr 183/Tyr 185)-R: (A,B,C) and JNK (FL): (D,E,F).

  • Western blot analysis of JNK3 expression in non-transfected: (A) and mouse JNK3 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).

  • Western blot analysis of JNK2 expression in non-transfected 293T: (A), human JNK2 transfected 293T: (B) and HeLa (C) whole cell lysates.

  • Western blot analysis of control (A,C) and UV-treated (B,D) JNK p46 (A,B) and JNK p54 (C,D) transfected COS cells.

  • Western blot analysis of JNK1 and JNK2 expression in K-562 (A), A-431 (B), NIH/3T3 (C), HeLa (D), RAW 264.7 (E) and Jurkat (F) whole cell lysates.

  • Intracellular FCM analysis of fixed and permeabilized A431 cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Antibodies tested include p-JNK (G-7): (A-D) and JNK1 (FL): (E-H).

Product Profile

Product Name JNK Antibody (FL) AC
Antibody Type Primary Antibodies
Modification Notes c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFFCELISA
recommended for detection of all JNK1, JNK2 and JNK3 p46 and p54 isoforms of mouse, rat, human, Drosophila, Xenopus, zebrafish and C. elegans origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity

HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified

Target Information

Alternative Names
epitope corresponding to amino acids 1-384 representing full length JNK1p46 of human origin
Tissue Specificity epitope corresponding to amino acids 1-384 representing full length JNK1p46 of human origin

Database Links

Entrez Gene 5599

Application

  • Application

    Antibodies tested include p-JNK (89.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Application

    Antibodies tested include p-JNK (29.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Application

    Antibodies tested include p-JNK (14.Thr 183/Tyr 185): (A,B,C) and JNK (FL): (D,E,F).

  • Application

    Antibodies tested include p-JNK (G-7): (A,B,C) and JNK (FL): (D,E,F).

  • Application

    Antibodies tested include p-JNK (Thr 183/Tyr 185)-R: (A,B,C) and JNK (FL): (D,E,F).

  • Application

    Western blot analysis of JNK3 expression in non-transfected: (A) and mouse JNK3 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).

  • Application

    Western blot analysis of JNK2 expression in non-transfected 293T: (A), human JNK2 transfected 293T: (B) and HeLa (C) whole cell lysates.

  • Application

    Western blot analysis of control (A,C) and UV-treated (B,D) JNK p46 (A,B) and JNK p54 (C,D) transfected COS cells.

  • Application

    Western blot analysis of JNK1 and JNK2 expression in K-562 (A), A-431 (B), NIH/3T3 (C), HeLa (D), RAW 264.7 (E) and Jurkat (F) whole cell lysates.

  • Application

    Intracellular FCM analysis of fixed and permeabilized A431 cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Application

    Antibodies tested include p-JNK (G-7): (A-D) and JNK1 (FL): (E-H).

Application Notes
recommended for detection of all JNK1, JNK2 and JNK3 p46 and p54 isoforms of mouse, rat, human, Drosophila, Xenopus, zebrafish and C. elegans origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM170849
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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