All products Antibodies LDL Receptor

LDL Receptor

Catalog Number：OM638919

  • Fig1: Western blot analysis of LDL Receptor on Hela (1) and MCF-7 (2) cell lysates using anti-LDL Receptor antibody at 1/1,000 dilution.

  • Fig2: ICC staining LDL Receptor in A549 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig3: ICC staining LDL Receptor in PC-3M cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-LDL Receptor antibody. Counter stained with hematoxylin.

  • Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-LDL Receptor antibody. Counter stained with hematoxylin.

  • Fig6: Flow cytometric analysis of Hela cells with LDL Receptor antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Product Profile

Product Name LDL Receptor
Antibody Type Primary Antibodies
Product description 
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDLR, LRP, Megalin, VLDLR, and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats, and an O-linked sugar domain. The LDL receptor is a cell surface transmembrane protein that mediates the uptake of low density lipoprotein and its degradation in the lysosome, which provides cholesterol to cells. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. Mutations in LDLR cause the autosomal dominant disease, familial hypercholesterolemia (FH), which promotes premature coronary atherosclerosis.
Immunogen 
Peptide.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity

HumanMouse
Concentration 1 mg/mL.

Target Information

Alternative Names
FH antibody FHC antibody LDL R antibody LDL receptor antibody LDLCQ2 antibody Ldlr antibody LDLR_HUMAN antibody Low Density Lipoprotein Receptor antibody Low density lipoprotein receptor class A domain containing protein 3 antibody Low density lipoprotein receptor familial hypercholesterolemia antibody Low-density lipoprotein receptor antibody
Molecular Weight(MW) 95/76 kDa(Predicted band size)
Cellular Localization Golgi apparatus. Plasma membrane. Endosome. Lysosome.

Database Links

SwissProt ID P01130
P35951

Application

  • Application

    Fig1: Western blot analysis of LDL Receptor on Hela (1) and MCF-7 (2) cell lysates using anti-LDL Receptor antibody at 1/1,000 dilution.

  • Application

    Fig2: ICC staining LDL Receptor in A549 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig3: ICC staining LDL Receptor in PC-3M cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-LDL Receptor antibody. Counter stained with hematoxylin.

  • Application

    Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-LDL Receptor antibody. Counter stained with hematoxylin.

  • Application

    Fig6: Flow cytometric analysis of Hela cells with LDL Receptor antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Positive Control Hela, MCF-7,A541, PC-3M, human liver cancer tissue, mouse testis tissue.
Application Notes
WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM638919
Submit an review for OM638919
  • Catalog Number: OM638919
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.