All products Antibodies LY75 Antibody (Center)

LY75 Antibody (Center)

Catalog Number：OM173724

  • Western blot analysis of LY75 Antibody (Center) (Cat. #AP8994c) in HL-60 cell line lysates (35ug/lane). LY75 (arrow) was detected using the purified Pab.

  • Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • LY75 Antibody (Center) (Cat. #AP8994c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Profile

Product Name LY75 Antibody (Center)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WBIHCFC
WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification

Target Information

Gene Synonyms
CD205
CLEC13B
Alternative Names
LY75
CD205
CLEC13B
Lymphocyte antigen 75
C-type lectin domain family 13 member B
DEC-205
gp200-MR6
CD_antigen=CD205
Flags: Precursor
Molecular Weight(MW) 198311 Da
Function
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes
Tissue Specificity Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells
Cellular Localization Membrane; Single-pass type I membrane protein (By similarity)

Database Links

Entrez Gene 4065

Application

  • Application

    Western blot analysis of LY75 Antibody (Center) (Cat. #AP8994c) in HL-60 cell line lysates (35ug/lane). LY75 (arrow) was detected using the purified Pab.

  • Application

    Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • Application

    LY75 Antibody (Center) (Cat. #AP8994c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM173724
  • Price: $336.00
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  • Lead time: 2~3 Week

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