All products Antibodies MyD88 Antibody (Center)

MyD88 Antibody (Center)

Catalog Number：OM214846

  • Western blot analysis of MyD88 Antibody (Center) in mouse lung tissue lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab.(2ug/ml)

  • Western blot analysis of MyD88 Antibody (Center) in HepG2 cell line lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab.

  • Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MyD88 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • MyD88 Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Profile

Product Name MyD88 Antibody (Center)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WBIHCFC
WB~~1:100~500 IHC~~1:10~50 FC~~1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification

Target Information

Alternative Names
MYD88
Myeloid differentiation primary response protein MyD88
Molecular Weight(MW) 33233 Da
Function
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity)
Tissue Specificity Ubiquitous.
Cellular Localization Cytoplasm.

Database Links

Entrez Gene 4615

Application

  • Application

    Western blot analysis of MyD88 Antibody (Center) in mouse lung tissue lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab.(2ug/ml)

  • Application

    Western blot analysis of MyD88 Antibody (Center) in HepG2 cell line lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab.

  • Application

    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MyD88 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • Application

    MyD88 Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
WB~~1:100~500 IHC~~1:10~50 FC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM214846
  • Price: $336.00
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  • Lead time: 2~3 Week

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