All products Antibodies N4BP1 Antibody (N-term)

N4BP1 Antibody (N-term)

Catalog Number:OM214945

  • N4BP1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the N4BP1 antibody detected the N4BP1 protein (arrow).

  • N4BP1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the N4BP1 antibody (N-term)) for immunohistochemistry. Clinical relevance has not been evaluated.

  • N4BP1 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Profile

Product Name N4BP1 Antibody (N-term)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WBIHCFC

WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:
Species Reactivity

Human

Concentration 1 mg/ml
Purification

Target Information

Gene Synonyms
KIAA0615
Alternative Names
N4BP1
KIAA0615
NEDD4-binding protein 1
Molecular Weight(MW) 100379 Da
Function
Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity)
Tissue Specificity Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary
Cellular Localization Nucleus, nucleolus (By similarity). Nucleus, PML body (By similarity). Note=Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated (By similarity)

Database Links

Entrez Gene 9683
Nucleotide Accession NP_694574.3

Application

  • Application

    N4BP1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the N4BP1 antibody detected the N4BP1 protein (arrow).

  • Application

    N4BP1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the N4BP1 antibody (N-term)) for immunohistochemistry. Clinical relevance has not been evaluated.

  • Application

    N4BP1 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM214945
  • Price: $336.00
  • Discount Price
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  • Store: In stock
  • Lead time: 2~3 Week
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