NKRF Antibody (C-term)

Product Profile

Product Name	NKRF Antibody (C-term)
Antibody Type	Primary Antibodies

Key Feature

Clonality	Polyclonal
Isotype	Ig
Host Species	Rabbit
Tested Applications	WBFC
	WB~~1:100~500 FC~~1:10~50:
Species Reactivity	Human
Concentration	1 mg/ml
Purification

Target Information

Gene Synonyms	ITBA4 NRF
Alternative Names	NKRF ITBA4 NRF NF-kappa-B-repressing factor Protein ITBA4 Transcription factor NRF
Molecular Weight(MW)	77673 Da
Function	Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription
Tissue Specificity	Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney
Cellular Localization	Nucleus, nucleolus.

Database Links

Entrez Gene	55922
Nucleotide Accession	NP_060014.2

Application

Application Notes	WB~~1:100~500 FC~~1:10~50:

Additional Information

Form	Liquid
Storage Instructions	For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

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• Data sheet for OM215384