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NME1 Antibody

Catalog Number：OM215445

  • Figure 1: Western blot analysis using NME1 mAb against NME1-hIgGFc transfected HEK293 cell lysate.

  • Figure 2:Immunofluorescence analysis of Hela cells using NME1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

  • Figure 3: Flow cytometric analysis of Jurkat cells using NME1 mouse mAb (green) and negative control (purple).

Product Profile

Product Name NME1 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 4B2
Host Species Mouse
Tested Applications

WBIFFC
WB~~1:500 - 2000. IF~~1:200 - 1000.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification

Target Information

Gene Synonyms
NDPKA
NM23
Alternative Names
NB
AWD
NBS
GAAD
NM23
NDPKA
NDPK-A
NM23-H1
NME1
Molecular Weight(MW) 17149 Da
Function
Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein- coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination
Tissue Specificity Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed
Cellular Localization Cytoplasm. Nucleus. Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA

Database Links

Entrez Gene 4830
Nucleotide Accession NP_937818.1

Application

  • Application

    Figure 1: Western blot analysis using NME1 mAb against NME1-hIgGFc transfected HEK293 cell lysate.

  • Application

    Figure 2:Immunofluorescence analysis of Hela cells using NME1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

  • Application

    Figure 3: Flow cytometric analysis of Jurkat cells using NME1 mouse mAb (green) and negative control (purple).

Application Notes
WB~~1:500 - 2000. IF~~1:200 - 1000.:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of human NME1 expressed in E. Coli.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM215445
  • Price: $396.00
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  • Lead time: 2~3 Week

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