Octamer transcription factor-4 (Oct-4) is a homeodomain transcription factor in the POU transcription factor family that specifically binds to the octamer motif (5'-ATTTCAT-3') (1). It is critical for early embryogenesis and for embryonic stem cell pluripotency, expressed mainly in the developing brain (1). OCT4 is a master regulator that affects the fate of pluripotent stem cells and germ cell precursors (2). For instance, the downregulation of Oct-4 triggers embryonic stem cell differentiation, simultaneous with gastrulation (3). It is also used as a marker for germ cell tumor diagnosis (4).
Immunogen
peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHCFCIP
WB:1:1,000 IP:1:10-100 IHC:1:100 FC:1:10-100
Species Reactivity
Human
Concentration
1 mg/mL.
Target Information
Alternative Names
Octamer binding transcription factor 4 antibody
MGC22487 antibody
Oct 3 antibody
Oct 4 antibody
Oct-3 antibody
Oct-4 antibody
OCT3 antibody
Oct4 antibody
Octamer binding protein 3 antibody
Octamer binding protein 4 antibody
Octamer binding transcription factor 3 antibody
Octamer-binding protein 3 antibody
Octamer-binding protein 4 antibody
Octamer-binding transcription factor 3 antibody
OTF 3 antibody
OTF 4 antibody
OTF-3 antibody
OTF3 antibody
OTF4 antibody
PO5F1_HUMAN antibody
POU class 5 homeobox 1 antibody
POU domain class 5 transcription factor 1 antibody
POU domain transcription factor OCT4 antibody
POU domain class 5 transcription factor 1 antibody
POU-type homeodomain-containing DNA-binding protein antibody
POU5F1 antibody
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