OCT-4

Catalog Number:OM638989

  • Fig1: Western blot analysis on (A) Seminoma, (B) NCCIT, and (C) HeLa cell lysates using anti-Oct-4

  • Fig2: Immunohistochemical staining of paraffin-embedded human ovarian dysgerminoma using anti-Oct-4 RabMAb.

Product Profile

Product Name OCT-4
Antibody Type Primary Antibodies
Product description
Octamer transcription factor-4 (Oct-4) is a homeodomain transcription factor in the POU transcription factor family that specifically binds to the octamer motif (5'-ATTTCAT-3') (1). It is critical for early embryogenesis and for embryonic stem cell pluripotency, expressed mainly in the developing brain (1). OCT4 is a master regulator that affects the fate of pluripotent stem cells and germ cell precursors (2). For instance, the downregulation of Oct-4 triggers embryonic stem cell differentiation, simultaneous with gastrulation (3). It is also used as a marker for germ cell tumor diagnosis (4).
Immunogen
peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHCFCIP

WB:1:1,000
IP:1:10-100
IHC:1:100
FC:1:10-100
Species Reactivity

Human

Concentration 1 mg/mL.

Target Information

Alternative Names
Octamer binding transcription factor 4 antibody
MGC22487 antibody
Oct 3 antibody
Oct 4 antibody
Oct-3 antibody
Oct-4 antibody
OCT3 antibody
Oct4 antibody
Octamer binding protein 3 antibody
Octamer binding protein 4 antibody
Octamer binding transcription factor 3 antibody
Octamer-binding protein 3 antibody
Octamer-binding protein 4 antibody
Octamer-binding transcription factor 3 antibody
OTF 3 antibody
OTF 4 antibody
OTF-3 antibody
OTF3 antibody
OTF4 antibody
PO5F1_HUMAN antibody
POU class 5 homeobox 1 antibody
POU domain class 5 transcription factor 1 antibody
POU domain transcription factor OCT4 antibody
POU domain
class 5
transcription factor 1 antibody
POU-type homeodomain-containing DNA-binding protein antibody
POU5F1 antibody
Molecular Weight(MW) 45kDa
Cellular Localization Cytoplasm, Nucleus

Database Links

SwissProt ID Q01860

Application

  • Application

    Fig1: Western blot analysis on (A) Seminoma, (B) NCCIT, and (C) HeLa cell lysates using anti-Oct-4

  • Application

    Fig2: Immunohistochemical staining of paraffin-embedded human ovarian dysgerminoma using anti-Oct-4 RabMAb.

Positive Control Hela, Seminoma, NCCIT.
Application Notes
WB:1:1,000
IP:1:10-100
IHC:1:100
FC:1:10-100

Additional Information

Form Liquid
Storage Instructions Store at -20 ℃. Stable for 12 months from date of receipt
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM638989
  • Price: $336.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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