All products Antibodies Rabbit anti-ARRB1 polyclonal antibody - middle region

Rabbit anti-ARRB1 polyclonal antibody - middle region

Catalog Number：OM105189

  • 0.2-1 ug/ml
    Positive Control: THP-1 cell lysate

Product Profile

Product Name Rabbit anti-ARRB1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-ARRB1 antibody: synthetic peptide directed towards the middle region of human ARRB1

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHorseHuman
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol ARRB1
Gene Synonyms
ARB1
ARR1
Gene Full Name Arrestin, beta 1
Gene Summary
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
Alternative Names
ARB1
ARR1
Molecular Weight(MW) 47kDa
Sequence 418 amino acids

Database Links

Entrez Gene 408
SwissProt ID P49407
Protein Accession NP_004032

Application

  • Western blot

    0.2-1 ug/ml
    Positive Control: THP-1 cell lysate

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105189
  • Price: $336.00
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  • Lead time: 2~3 Week

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