Rabbit anti-BAK1 polyclonal antibody - N-terminal region

Product Profile

Product Name	Rabbit anti-BAK1 polyclonal antibody - N-terminal region
Antibody Type	Primary Antibodies

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	BAK1
Gene Synonyms	BAK BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887
Gene Full Name	BCL2-antagonist/killer 1
Gene Summary	BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Alternative Names	BAK BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887
Molecular Weight(MW)	23kDa
Sequence	211 amino acids

Database Links

Entrez Gene	578
SwissProt ID	Q16611
Protein Accession	NP_001179

Application

Application Notes	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM105184