All products Antibodies Rabbit anti-BCL2L1 polyclonal antibody - N-terminal region

Rabbit anti-BCL2L1 polyclonal antibody - N-terminal region

Catalog Number：OM105186

  • 2.5ug/ml
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate

Product Profile

Product Name Rabbit anti-BCL2L1 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-BCL2L1 antibody: synthetic peptide directed towards the N terminal of human BCL2L1

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHumanMousePigRabbitRatSheep
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol BCL2L1
Gene Synonyms
BCL-XL/S
BCL2L
BCLX
Bcl-X
DKFZp781P2092
bcl-xL
bcl-xS
BCLXL
BCLXS
PPP1R52
Gene Full Name BCL2-like 1
Gene Summary
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Alternative Names
BCL-XL/S
BCL2L
BCLX
Bcl-X
DKFZp781P2092
bcl-xL
bcl-xS
BCLXL
BCLXS
PPP1R52
Molecular Weight(MW) 26kDa
Sequence 233 amino acids

Database Links

Entrez Gene 598
SwissProt ID Q07817
Protein Accession NP_612815

Application

  • Western blot

    2.5ug/ml
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105186
  • Price: $336.00
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  • Lead time: 2~3 Week

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