Rabbit anti-Clk4 polyclonal antibody - N-terminal region

Product Profile

Product Name	Rabbit anti-Clk4 polyclonal antibody - N-terminal region
Antibody Type	Primary Antibodies

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	MouseHuman
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	Clk4
Gene Synonyms	AI987988 C85119
Gene Full Name	CDC like kinase 4
Gene Summary	Clk4 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Clk4 phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Clk4 phosphorylates SRSF1 and SRSF3. Clk4 is required for the regulation of alternative splicing of MAPT/TAU. Clk4 regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Alternative Names	AI987988 C85119
Molecular Weight(MW)	57kDa
Sequence	481 amino acids

Database Links

Entrez Gene	12750
SwissProt ID	O35493
Protein Accession	NP_031740

Application

Application Notes	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM105194