Rabbit anti-DVL1 polyclonal antibody - C-terminal region
Catalog Number:OM105628
Product Profile
Product Name
Rabbit anti-DVL1 polyclonal antibody - C-terminal region
Antibody Type
Primary Antibodies
Immunogen
The immunogen for anti-DVL1 antibody: synthetic peptide directed towards the C terminal of human DVL1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB :1:500~1:2000Notes :Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Bovine Dog Horse Human Mouse Pig Rat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
DVL1
Gene Synonyms
DVL MGC54245 DVL1L1
Gene Full Name
Dishevelled, dsh homolog 1 (Drosophila)
Gene Summary
DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.
Alternative Names
DVL MGC54245 DVL1L1
Molecular Weight(MW)
73kDa
Sequence
670 amino acids
Database Links
Application
Western blot
2.5ug/ml Positive Control: K562 cell lysate
Application Notes
WB :1:500~1:2000Notes :Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer
phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
Catalog Number:
OM105628
Price:
$ 336.00
Discount Price
Size:
100ug
Store:
In stock
Lead time:
2~3 Week
Quantity:
-
+
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Equatorial Guinea
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