All products Antibodies Rabbit anti-HMGB2 polyclonal antibody - C-terminal region

Rabbit anti-HMGB2 polyclonal antibody - C-terminal region

Catalog Number：OM105555

  • 0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate

Product Profile

Product Name Rabbit anti-HMGB2 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-HMGB2 antibody: synthetic peptide directed towards the C terminal of human HMGB2

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHumanMousePigRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol HMGB2
Gene Synonyms
HMG2
Gene Full Name High mobility group box 2
Gene Summary
This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names
HMG2
Molecular Weight(MW) 24kDa
Sequence 209 amino acids

Database Links

Entrez Gene 3148
SwissProt ID P26583
Protein Accession NP_002120

Application

  • Immunohistochemical

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate

Application Notes
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105555
  • Price: $336.00
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