All products Antibodies Rabbit anti-PHOX2A polyclonal antibody - N-terminal region

Rabbit anti-PHOX2A polyclonal antibody - N-terminal region

Catalog Number：OM105621

  • 0.2-1 ug/ml
    ELISA Titer: 1:12500
    Positive Control: Human Stomach

Product Profile

Product Name Rabbit anti-PHOX2A polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-PHOX2A antibody: synthetic peptide directed towards the N terminal of human PHOX2A

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogPigRabbitRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol PHOX2A
Gene Synonyms
ARIX
CFEOM2
FEOM2
MGC52227
NCAM2
PMX2A
Gene Full Name Paired-like homeobox 2a
Gene Summary
PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names
ARIX
CFEOM2
FEOM2
MGC52227
NCAM2
PMX2A
Molecular Weight(MW) 30kDa
Sequence 284 amino acids

Database Links

Entrez Gene 401
SwissProt ID O14813
Protein Accession NP_005160

Application

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:12500
    Positive Control: Human Stomach

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105621
  • Price: $336.00
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  • Lead time: 2~3 Week

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