Rabbit anti-TNFRSF10A polyclonal antibody - C-terminal region

Product Profile

Product Name	Rabbit anti-TNFRSF10A polyclonal antibody - C-terminal region
Antibody Type	Primary Antibodies

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	TNFRSF10A
Gene Synonyms	APO2 CD261 DR4 MGC9365 TRAILR-1 TRAILR1
Gene Full Name	Tumor necrosis factor receptor superfamily, member 10a
Gene Summary	This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Alternative Names	APO2 CD261 DR4 MGC9365 TRAILR-1 TRAILR1
Molecular Weight(MW)	50kDa
Sequence	468 amino acids

Database Links

Entrez Gene	8797
SwissProt ID	O00220
Protein Accession	NP_003835

Application

Application Notes	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM105193