All products Antibodies Tyrosine Hydroxylase

Tyrosine Hydroxylase

Catalog Number：OM638957

  • Fig1: Western blot analysis of Tyrosine Hydroxylase on PC-12 cell lysate using anti-Tyrosine Hydroxylase antibody at 1/1,000 dilution.

  • Fig2: Western blot analysis of Tyrosine Hydroxylase on mouse brain tissue (1) and MCF-7 cell (2) lysate using anti-Tyrosine Hydroxylase antibody at 1/500 dilution.

  • Fig3: ICC staining Tyrosine Hydroxylase in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig4: ICC staining Tyrosine Hydroxylase in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig5: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Tyrosine Hydroxylase antibody. Counter stained with hematoxylin.

  • Fig6: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Tyrosine Hydroxylase antibody. Counter stained with hematoxylin.

  • Fig7: Flow cytometric analysis of SH-SY5Y cells with Tyrosine Hydroxylase antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Product Profile

Product Name Tyrosine Hydroxylase
Antibody Type Primary Antibodies
Product description 
The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.
Immunogen 
Recombinant protein

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity

HumanMouseRat
Concentration 1 mg/mL.

Target Information

Alternative Names
Dystonia 14 antibody DYT14 antibody DYT5b antibody EC 1.14.16.2 antibody OTTHUMP00000011225 antibody OTTHUMP00000011226 antibody ple antibody Protein Pale antibody TH antibody The antibody TY3H_HUMAN antibody TYH antibody Tyrosine 3 hydroxylase antibody Tyrosine 3 monooxygenase antibody Tyrosine 3-hydroxylase antibody Tyrosine 3-monooxygenase antibody Tyrosine hydroxylase antibody
Molecular Weight(MW) 45/58 kDa
Cellular Localization Cytoplasm. Nucleus.

Database Links

SwissProt ID P07101
P24529
P04177

Application

  • Application

    Fig1: Western blot analysis of Tyrosine Hydroxylase on PC-12 cell lysate using anti-Tyrosine Hydroxylase antibody at 1/1,000 dilution.

  • Application

    Fig2: Western blot analysis of Tyrosine Hydroxylase on mouse brain tissue (1) and MCF-7 cell (2) lysate using anti-Tyrosine Hydroxylase antibody at 1/500 dilution.

  • Application

    Fig3: ICC staining Tyrosine Hydroxylase in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig4: ICC staining Tyrosine Hydroxylase in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig5: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Tyrosine Hydroxylase antibody. Counter stained with hematoxylin.

  • Application

    Fig6: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Tyrosine Hydroxylase antibody. Counter stained with hematoxylin.

  • Application

    Fig7: Flow cytometric analysis of SH-SY5Y cells with Tyrosine Hydroxylase antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Positive Control PC-12, mouse brain tissue, MCF-7, N2A, SHG-44, rat brain tissue, SH-SY5Y.
Application Notes
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Additional Information

Form Liquid
Storage Instructions Store at +4℃after thawing. Aliquot store at -20℃or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638957
  • Price: $336.00
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  • Lead time: 4~6 Week

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