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Rabbit anti-RIPK3 polyclonal antibody - N-terminal region

Catalog Number:OM105381
OM105381
Discount Price
OM105381-100ul
1~2 Week
100ul
OM105381-50ul
50ul
OM105381-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-RIPK3 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias RIP3, RIP3 beta, RIP3 gamma
Immunogen The immunogen for anti-RIPK3 antibody: synthetic peptide directed towards the N terminal of human RIPK3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePig
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol RIPK3
Gene Synonyms RIP3
RIP3 beta
RIP3 gamma
Gene Full Name Receptor-interacting serine-threonine kinase 3
Gene Summary RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Alternative Names RIP3
RIP3 beta
RIP3 gamma
Molecular Weight(MW) 57kDa
Sequence 518 amino acids
Database Links
Entrez Gene 11035
SwissProt ID Q9Y572
Protein Accession NP_006862
Application

Immunohistochemical

Immunohistochemical

Western blot

1.25ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate
Application Notes IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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