Western blot
0.2-1 ug/mlPositive Control: Jurkat cell lysateImmunohistochemical
Immunohistochemical| Product Name | Rabbit anti-CSEN polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSEN, DREAM, KCHIP3 |
| Immunogen | The immunogen for anti-CSEN antibody: synthetic peptide directed towards the N terminal of human CSEN |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CSEN |
|---|---|
| Gene Synonyms | CSEN DREAM KCHIP3 |
| Gene Full Name | Kv channel interacting protein 3, calsenilin |
| Gene Summary | CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. |
| Alternative Names | CSEN DREAM KCHIP3 |
| Molecular Weight(MW) | 29kDa |
| Sequence | 256 amino acids |
Western blot
0.2-1 ug/mlPositive Control: Jurkat cell lysate
Immunohistochemical
Immunohistochemical| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
