| Gene Symbol |
PARP3
|
| Gene Synonyms |
IRT1 ADPRT3 ADPRTL2 ADPRTL3 PADPRT-3 |
| Gene Full Name |
Poly (ADP-ribose) polymerase family, member 3 |
| Gene Summary |
PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Alternative Names |
IRT1 ADPRT3 ADPRTL2 ADPRTL3 PADPRT-3 |
| Molecular Weight(MW) |
59kDa |
| Sequence |
532 amino acids |