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XRCC5 antibody - C-terminal region

Catalog Number:OM106671
OM106671
Discount Price
OM106671-100ul
1~2 Week
100ul
OM106671-50ul
50ul
OM106671-20ul
20ul
1~2 Week
Product Profile
Product Name XRCC5 antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-XRCC5 antibody: synthetic peptide directed towards the C terminal of human XRCC5
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB,IHC
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rabbit,Rat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol XRCC5
Gene Synonyms KU80
KUB2
Ku86
NFIV
KARP1
KARP-1
Gene Full Name X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Gene Summary XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alternative Names KU80
KUB2
Ku86
NFIV
KARP1
KARP-1
Molecular Weight(MW) 83kDa
Sequence 732 amino acids
Database Links
Entrez Gene 7520
SwissProt ID Q4VBQ5
Protein Accession NP_066964
Application

Immunohistochemical

Human lung adenocarcinoma cell line A549
Primary Antibody Dilution :
1:100
Secondary Antibody :
Goat anti-rabbit AlexaFluor 488
Secondary Antibody Dilution :
1:400
Color/Signal Descriptions :
XRCC5: Green DAPI:Blue
Gene Name :
XRCC5
Submitted by :
Dr. Crissy Dudgeon, Ph.D., CINJ

Immunohistochemical

Immunoblot

1. 30 ug MiaPaca-2 cell lysate
2. 30 ug Panc-1 cell lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Goat anti-Rabbit HRP
Secondary Antibody Dilution:
1:4000
Gene Name:
XRCC5
Submitted by:
Dr. Crissy Dudgeon, Ph.D., CINJ

Western blot

1.25ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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