Immunoblot
100 ug CHO cell lysatePrimary Antibody Dilution: 1:1000Secondary Antibody: Goat anti-rabbit HRPSecondary Antibody Dilution: 1:25000Gene Name: KCNQ4Submitted by: AnonymousWestern blot
0.2-1 ug/mlPositive Control: HT1080 cell lysate| Product Name | Rabbit anti-KCNQ4 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DFNA2, KV7.4, DFNA2A |
| Immunogen | The immunogen for anti-KCNQ4 antibody: synthetic peptide directed towards the middle region of human KCNQ4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KCNQ4 |
|---|---|
| Gene Synonyms | DFNA2 KV7.4 DFNA2A |
| Gene Full Name | Potassium voltage-gated channel, KQT-like subfamily, member 4 |
| Gene Summary | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | DFNA2 KV7.4 DFNA2A |
| Molecular Weight(MW) | 77kDa |
| Sequence | 695 amino acids |
Immunoblot
100 ug CHO cell lysatePrimary Antibody Dilution: 1:1000Secondary Antibody: Goat anti-rabbit HRPSecondary Antibody Dilution: 1:25000Gene Name: KCNQ4Submitted by: Anonymous
Western blot
0.2-1 ug/mlPositive Control: HT1080 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM107210