Western blot
Host: Rabbit Target Name: Atf7ip Sample Tissue: Mouse Lung lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Atf7ip Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 2610204M12Rik, AM, Mcaf1 |
| Immunogen | The immunogen for Anti-Atf7ip antibody is: synthetic peptide directed towards the middle region of Mouse Atf7ip |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Atf7ip |
|---|---|
| Gene Synonyms | 2610204M12Rik AM Mcaf1 |
| Gene Full Name | activating transcription factor 7 interacting protein |
| Gene Summary | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity. |
| Alternative Names | 2610204M12Rik AM Mcaf1 |
| Molecular Weight(MW) | 138kDa |
| Sequence | 1306 amino acids |
Western blot
Host: Rabbit Target Name: Atf7ip Sample Tissue: Mouse Lung lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
