Western blot
0.2-1 ug/mlPositive Control: Mouse LungWestern blot
0.2-1 ug/mlPositive Control: Mouse Lung| Product Name | Rabbit anti-Fbxw7 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 1110001A17Rik, AGO, Cdc4, Fbw7, Fbwd6, Fbx30, Fbxo30, Fbxw6, SEL-10 |
| Immunogen | The immunogen for anti-Fbxw7 antibody: synthetic peptide directed towards the middle region of mouse Fbxw7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRabbitZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Fbxw7 |
|---|---|
| Gene Synonyms | 1110001A17Rik AGO Cdc4 Fbw7 Fbwd6 Fbx30 Fbxo30 Fbxw6 SEL-10 |
| Gene Full Name | F-box and WD-40 domain protein 7 |
| Gene Summary | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. |
| Alternative Names | 1110001A17Rik AGO Cdc4 Fbw7 Fbwd6 Fbx30 Fbxo30 Fbxw6 SEL-10 |
| Molecular Weight(MW) | 70kDa |
| Sequence | 629 amino acids |
Western blot
0.2-1 ug/mlPositive Control: Mouse Lung
Western blot
0.2-1 ug/mlPositive Control: Mouse Lung| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
