Western blot
2.5ug/ml| Product Name | TIMELESS antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-TIMELESS antibody: synthetic peptide directed towards the C terminal of human TIMELESS |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TIMELESS |
|---|---|
| Gene Synonyms | TIM TIM1 hTIM |
| Gene Full Name | Timeless homolog (Drosophila) |
| Gene Summary | The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. |
| Alternative Names | TIM TIM1 hTIM |
| Molecular Weight(MW) | 139kDa |
| Sequence | 1208 amino acids |
Western blot
2.5ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
