WB
Western blot analysis of Timeless expression in BxPC3 (A) whole cell lysates.| Product Name | Anti-Timeless Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant fusion protein of human Timeless. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TIMELESS |
|---|---|
| Gene Synonyms | TIM TIM1 hTIM FASPS4 |
| Gene Full Name | timeless circadian regulator |
| Gene Summary | The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014] |
| Alternative Names | TIM TIM1 TIMELESS1 Protein timeless homolog hTIM |
| Molecular Weight(MW) | 138 kDa(Observed band size: 160 kDa) |
| Cellular Localization | Chromosome,Nucleus. |
WB
Western blot analysis of Timeless expression in BxPC3 (A) whole cell lysates.| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
