Application
WB Suggested Anti-OPTN Antibody Titration: 0.2-1 ug/mlApplication
Rabbit Anti-OPTN Antibody| Product Name | OPTN antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-OPTN antibody: synthetic peptide directed towards the N terminal of human OPTN |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Horse,Human,Pig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OPTN |
|---|---|
| Gene Synonyms | OPTN |
| Gene Full Name | Optineurin |
| Gene Summary | OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Alternative Names | FIP2 GLC1E HIP7 HYPL NRP TFIIIA-INTP ALS12 |
| Molecular Weight(MW) | 66kDa |
| Sequence | 577 amino acids |
| Entrez Gene | 10133 |
|---|---|
| SwissProt ID | Q96CV9 |
| Protein Accession | NP_001008214 |
Application
WB Suggested Anti-OPTN Antibody Titration: 0.2-1 ug/ml
Application
Rabbit Anti-OPTN Antibody| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM109275