| Product Name | Anti-Phospho-Optineurin (Ser177) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser177 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OPTN |
|---|---|
| Gene Synonyms | NRP FIP2 HIP7 HYPL ALS12 GLC1E TFIIIA-INTP |
| Gene Full Name | optineurin |
| Gene Summary | This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Alternative Names | 14.7K interacting protein antibody Ag9 C5 antibody ALS12 antibody E3 14.7K interacting protein antibody E3-14.7K-interacting protein antibody FIP 2 antibody FIP-2 antibody FIP2 antibody Glaucoma 1 open angle E (adult onset) antibody Glaucoma 1 open angle E antibody GLC1E antibody HIP 7 antibody HIP-7 antibody HIP7 antibody Huntingtin interacting protein 7 antibody Huntingtin interacting protein HYPL antibody Huntingtin interacting protein L antibody Huntingtin yeast partner L antibody Huntingtin-interacting protein 7 antibody Huntingtin-interacting protein L antibody HYPL antibody Injury inducible protein I 55 antibody NEMO related protein antibody NEMO-related protein antibody NRP antibody Optic neuropathy inducing protein antibody Optic neuropathy-inducing protein antibody Optineurin antibody OPTN antibody OPTN_HUMAN antibody TFIIIA IntP antibody TFIIIA-IntP antibody Transcription factor IIIA interacting protein antibody Transcription factor IIIA-interacting protein antibody Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody |
| Molecular Weight(MW) | 66 kDa |
| Cellular Localization | Cytoplasm,Cytoplasmic vesicle,Endosome,Golgi apparatus. |
| SwissProt ID | Q96CV9 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
