| Product Name | Rabbit anti-ZNF496 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NIZP1, ZFP496, ZKSCAN17 |
| Immunogen | The immunogen for anti-ZNF496 antibody: synthetic peptide directed towards the N terminal of human ZNF496 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorsePigSheep |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ZNF496 |
|---|---|
| Gene Synonyms | NIZP1 ZFP496 ZKSCAN17 |
| Gene Full Name | Zinc finger protein 496 |
| Gene Summary | ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif. |
| Alternative Names | NIZP1 ZFP496 ZKSCAN17 |
| Molecular Weight(MW) | 67kDa |
| Sequence | 587 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM109394