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RNF34 antibody - middle region

Catalog Number:OM109617
OM109617
Discount Price
OM109617-100ul
1~2 Week
100ul
OM109617-50ul
50ul
OM109617-20ul
20ul
1~2 Week
Product Profile
Product Name RNF34 antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-RNF34 antibody: synthetic peptide directed towards the middle region of human RNF34
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RNF34
Gene Synonyms FLJ21786
RFI
RIF
RIFF
hRFI
CARP1
CARP-1
Gene Full Name Ring finger protein 34, E3 ubiquitin protein ligase
Gene Summary RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis.The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative Names FLJ21786
RFI
RIF
RIFF
hRFI
CARP1
CARP-1
Molecular Weight(MW) 42kDa
Sequence 372 amino acids
Database Links
Entrez Gene 80196
SwissProt ID Q969K3
Protein Accession NP_079402
Application

Western blot

0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Muscle
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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