Western blot
2.5ug/ml| Product Name | PRMT5 antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PRMT5 antibody: synthetic peptide directed towards the N terminal of human PRMT5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Dog,Horse,Human,Pig,Rabbit,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PRMT5 |
|---|---|
| Gene Synonyms | JBP1 SKB1 IBP72 SKB1Hs HRMT1L5 |
| Gene Full Name | Protein arginine methyltransferase 5 |
| Gene Summary | PRMT5 methylates specific arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3 to monomethylarginine and to symmetrical dimethylarginines (sDMAs). It methylates SUPT5H. PRMT5 plays a role in the assembly of snRNP core particles and may play a role in cytokine-activated transduction pathways. It negatively regulates cyclin E1 promoter activity and cellular proliferation and May regulate the SUPT5H transcriptional elongation properties. It may be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. PRMT5 methylates histone H2A/H4 'Arg-3' during germ cell development and methylates histone H3 'Arg-8', which may repress transcription. |
| Alternative Names | JBP1 SKB1 IBP72 SKB1Hs HRMT1L5 |
| Molecular Weight(MW) | 68kDa |
| Sequence | 620 amino acids |
| Entrez Gene | 10419 |
|---|---|
| SwissProt ID | O14744 |
| Protein Accession | NP_001034708 |
Western blot
2.5ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
