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PDCD8 antibody - C-terminal region
Catalog Number:OM109641
OM109641
Discount Price
OM109641-100ul
1~2 Week
100ul
OM109641-50ul
50ul
OM109641-20ul
20ul
1~2 Week
Product Profile
Product Name PDCD8 antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-PDCD8 antibody: synthetic peptide directed towards the C terminal of human PDCD8
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Zebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PDCD8
Gene Synonyms AIF
PDCD8
COXPD6
Gene Full Name Apoptosis-inducing factor, mitochondrion-associated, 1
Gene Summary AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alternative Names AIF
PDCD8
COXPD6
Molecular Weight(MW) 36kDa
Sequence 326 amino acids
Database Links
Entrez Gene 9131
SwissProt ID O95831-2
Protein Accession NP_665812
Application

Western blot

0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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