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Rabbit anti-AIFM1 polyclonal antibody - middle region
Catalog Number:OM121847
OM121847
Discount Price
OM121847-100ul
1~2 Week
100ul
OM121847-50ul
50ul
OM121847-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-AIFM1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias AIF, MGC111425, PDCD8, COXPD6
Immunogen The immunogen for anti-AIFM1 antibody: synthetic peptide directed towards the middle region of human AIFM1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol AIFM1
Gene Synonyms AIF
MGC111425
PDCD8
COXPD6
Gene Full Name Apoptosis-inducing factor, mitochondrion-associated, 1
Gene Summary AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alternative Names AIF
MGC111425
PDCD8
COXPD6
Molecular Weight(MW) 67kDa
Sequence 613 amino acids
Database Links
Entrez Gene 9131
SwissProt ID O95831
Protein Accession NP_004199
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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