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Rabbit anti-SF3B4 polyclonal antibody - N-terminal region

Catalog Number:OM109923
OM109923
Discount Price
OM109923-100ul
1~2 Week
100ul
OM109923-50ul
50ul
OM109923-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SF3B4 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias AFD1, Hsh49, SAP49, SF3b49
Immunogen The immunogen for anti-SF3B4 antibody: synthetic peptide directed towards the N terminal of human SF3B4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SF3B4
Gene Synonyms AFD1
Hsh49
SAP49
SF3b49
Gene Full Name Splicing factor 3b, subunit 4, 49kDa
Gene Summary SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alternative Names AFD1
Hsh49
SAP49
SF3b49
Molecular Weight(MW) 47kDa
Sequence 424 amino acids
Database Links
Entrez Gene 10262
SwissProt ID Q15427
Protein Accession NP_005841
Application

Western blot

0.2-1 ug/mlPositive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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