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STAU1 antibody - N-terminal region

Catalog Number:OM110077
OM110077
Discount Price
OM110077-100ul
1~2 Week
100ul
OM110077-50ul
50ul
OM110077-20ul
20ul
1~2 Week
Product Profile
Product Name STAU1 antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-STAU1 antibody: synthetic peptide directed towards the N terminal of human STAU1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB,IHC
Species Reactivity Bovine,Guinea Pig,Horse,Human,Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol STAU1
Gene Synonyms FLJ25010
STAU
Gene Full Name Staufen, RNA binding protein, homolog 1 (Drosophila)
Gene Summary This protein is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are haracterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translationStaufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Alternative Names FLJ25010
STAU
Molecular Weight(MW) 63kDa
Sequence 577 amino acids
Database Links
Entrez Gene 6780
SwissProt ID O95793
Protein Accession NP_059347
Application

Western blot

Host: Rabbit
Target Name: STAU1
Sample Tissue: 293T
Antibody Dilution: 1.0ug/ml

Immunohistochemical

Paraffin embedded heart tissue, tested with an antibody Dilution of 5 ug/ml.

Western blot

Host: Rabbit
Target Name: STAU1
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit
Target Name: STAU1
Sample Tissue: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit
Target Name: STAU1
Sample Tissue: Hela
Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit
Target Name: STAU1
Sample Tissue: MCF7
Antibody Dilution: 1.0ug/ml
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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