Application
Western blot analysis of STAU1 in rat brain tissue lysate with STAU1 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of STAU1 in Human Brain cells with STAU1 antibody at 20 μg/mL.Application
Immunohistochemistry of STAU1 in human brain tissue with STAU1 antibody at 10 μg/mL.| Product Name | STAU1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAU1 Antibody: STAU, STAU, Double-stranded RNA-binding protein Staufen homolog 1 |
| Product description | STAU1 Antibody: STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.1) Marion RM, Fortes P, Peloso A, et al. A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol. Cell. Biol.1999; 19:2212-9. |
| Immunogen | STAU1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human STAU1. The immunogen is located within the last 50 amino acids of STAU1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| STAU1 antibody can be used for detection of STAU1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STAU1 |
|---|---|
| Alternative Names | STAU1 Antibody: STAU STAU Double-stranded RNA-binding protein Staufen homolog 1 |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
Application
Western blot analysis of STAU1 in rat brain tissue lysate with STAU1 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of STAU1 in Human Brain cells with STAU1 antibody at 20 μg/mL.
Application
Immunohistochemistry of STAU1 in human brain tissue with STAU1 antibody at 10 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | STAU1 antibody can be used for detection of STAU1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | STAU1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | STAU1 Antibody is supplied in PBS containing 0.02% sodium azide. |
