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Rabbit anti-STAU1 polyclonal antibody - N-terminal region

Catalog Number:OM110079
OM110079
Discount Price
OM110079-100ul
1~2 Week
100ul
OM110079-50ul
50ul
OM110079-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-STAU1 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias FLJ25010, STAU
Immunogen The immunogen for anti-STAU1 antibody: synthetic peptide directed towards the N terminal of human STAU1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineGuinea PigHorseHuman
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol STAU1
Gene Synonyms FLJ25010
STAU
Gene Full Name Staufen, RNA binding protein, homolog 1 (Drosophila)
Gene Summary This protein is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are haracterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translationStaufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Alternative Names FLJ25010
STAU
Molecular Weight(MW) 63kDa
Sequence 577 amino acids
Database Links
Entrez Gene 6780
SwissProt ID O95793
Protein Accession NP_059347
Application

Western blot

Host: Rabbit Target Name: STAU1 Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: STAU1 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: STAU1 Sample Tissue: MCF7 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: STAU1 Sample Tissue: Hela Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: STAU1 Sample Tissue: HepG2 Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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