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TPM1 antibody - N-terminal region

Catalog Number:OM110368
OM110368
Discount Price
OM110368-100ul
1~2 Week
100ul
OM110368-50ul
50ul
OM110368-20ul
20ul
1~2 Week
Product Profile
Product Name TPM1 antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-TPM1 antibody: synthetic peptide directed towards the N terminal of human TPM1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB,IHC
Species Reactivity Bovine,Dog,Guinea Pig,Human,Mouse,Pig,Rabbit,Rat,Sheep,Zebra Fish
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TPM1
Gene Synonyms CMH3
TMSA
TPM1-alpha
CMD1Y
C15orf13
HTM-alpha
Gene Full Name Tropomyosin 1 (alpha)
Gene Summary TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alternative Names CMH3
TMSA
TPM1-alpha
CMD1Y
C15orf13
HTM-alpha
Molecular Weight(MW) 31kDa
Sequence 284 amino acids
Database Links
Entrez Gene 7168
SwissProt ID P09493
Protein Accession NP_000357
Application

Western blot

1.25ug/ml
Positive Control: HepG2 cell lysate

Western blot

Host: Rabbit
Target Name:TPM1
Sample Tissue:HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration:1.25ug/mL
Peptide Concentration: 1.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12%
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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