| Product Name | Tropomyosin-1a (Ser 283) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Tropomyosin-1 (alpha), phospho serine 283, CMH3, TMSA, CMD1Y, LVNC9, C15orf13, HTM-alpha |
| Product description | Tropomyosin (Tpm-1)consists of a family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction..1) Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat. Yuan, C., Sheng, Q., Tang, H.,Tixue, L., Zeng, R., and Solaro, R.J.. Am J Physiol Heart Circ Physiol.2008; 295: H647-H656. |
| Immunogen | A synthetic phosphopeptide corresponding to the region surrounding S283. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| ELISA, Western (immuno) blotting, Immunostaining (in testing): |
|
| Species Reactivity | ChickenHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TPM1 |
|---|---|
| Alternative Names | Tropomyosin-1 (alpha) phospho serine 283 CMH3 TMSA CMD1Y LVNC9 C15orf13 HTM-alpha |
| Application Notes | ELISA, Western (immuno) blotting, Immunostaining (in testing): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
