Western blot
Sample Type: Equine Cartilage Explants Primary Dilution: 1:1000 Secondary: Abcam ab97200 (Dilution: 1:20,000)Western blot
MMP3 antibody - middle region validated by WB using Equine Cartilage Explants at 1:1000.Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate| Product Name | Rabbit anti-MMP3 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6 |
| Immunogen | The immunogen for anti-MMP3 antibody: synthetic peptide directed towards the middle region of human MMP3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MMP3 |
|---|---|
| Gene Synonyms | MGC126102 MGC126103 MGC126104 MMP-3 SL-1 STMY STMY1 STR1 CHDS6 |
| Gene Full Name | Matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| Gene Summary | MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | MGC126102 MGC126103 MGC126104 MMP-3 SL-1 STMY STMY1 STR1 CHDS6 |
| Molecular Weight(MW) | 43kDa |
| Sequence | 477 amino acids |
Western blot
Sample Type: Equine Cartilage Explants Primary Dilution: 1:1000 Secondary: Abcam ab97200 (Dilution: 1:20,000)
Western blot
MMP3 antibody - middle region validated by WB using Equine Cartilage Explants at 1:1000.
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
