Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Small Intestine| Product Name | Rabbit anti-Fbxo2 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FBG1, FBX2, Fbs1, Fbs2, MGC54895, NFB42, Prpl4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Fbxo2 |
|---|---|
| Gene Synonyms | FBG1 FBX2 Fbs1 Fbs2 MGC54895 NFB42 Prpl4 |
| Gene Full Name | F-box protein 2 |
| Gene Summary | Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type. |
| Alternative Names | FBG1 FBX2 Fbs1 Fbs2 MGC54895 NFB42 Prpl4 |
| Molecular Weight(MW) | 34kDa |
| Sequence | 297 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Small Intestine| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
