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Rabbit anti-SGCB polyclonal antibody - middle region

Catalog Number:OM111701
OM111701
Discount Price
OM111701-100ul
1~2 Week
100ul
OM111701-50ul
50ul
OM111701-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SGCB polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias A3b, LGMD2E, SGC
Immunogen The immunogen for anti-SGCB antibody: synthetic peptide directed towards the middle region of human SGCB
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Species Reactivity BovineGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SGCB
Gene Synonyms A3b
LGMD2E
SGC
Gene Full Name Sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Summary SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442
Alternative Names A3b
LGMD2E
SGC
Molecular Weight(MW) 35kDa
Sequence 318 amino acids
Database Links
Entrez Gene 6443
SwissProt ID Q16585
Protein Accession NP_000223
Application

Western blot

Host: Rabbit Target Name: SGCB Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml

Western blot

1 ug/mlPositive Control: Human heart
Application Notes WB:1:500~1:2000
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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