Mouse monoclonal [GC25] to Guanylate CyclaseGuanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.
Immunogen
Recombinant full length protein: Recombinant human soluble guanylate cyclase alpha1 beta1 heterodimer.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
GC25
Host Species
Mouse
Tested Applications
ELISAIHCWB
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 70 kDa. Optimal dilutions/concentrations should be determined by the end user.:
recognizes the beta subunit of Human Soluble Guanylate Cyclase.
Cellular Localization
Cytoplasmic
Application
Application
Application
Application Notes
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 70 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.