Application
Antibody used in WB on Human Heart at 0.2-1 ug/ml.Application
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.| Product Name | SGCB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).1) Draviam, R.A., (2006) Muscle Nerve 34 (6), 691-701. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SGCB. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| SGCB antibody can be used for detection of SGCB by ELISA at 1:312500. SGCB antibody can be used for detection of SGCB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SGCB |
|---|---|
| Alternative Names | SGCB A3b LGMD2E SGC |
| Molecular Weight(MW) | 35 kDa |
Application
Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Application
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.| Positive Control | 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate |
|---|---|
| Application Notes | SGCB antibody can be used for detection of SGCB by ELISA at 1:312500. SGCB antibody can be used for detection of SGCB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store SGCB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
