Immunohistochemical
ImmunohistochemicalWestern blot
0.2-1 ug/mlPositive Control: HepG2 cell lysate| Product Name | Rabbit anti-HFE polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2 |
| Immunogen | The immunogen for anti-HFE antibody: synthetic peptide directed towards the C terminal of human HFE |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanPigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HFE |
|---|---|
| Gene Synonyms | HFE1 HH HLA-H MGC103790 dJ221C16.10.1 MVCD7 TFQTL2 |
| Gene Full Name | Hemochromatosis |
| Gene Summary | HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. |
| Alternative Names | HFE1 HH HLA-H MGC103790 dJ221C16.10.1 MVCD7 TFQTL2 |
| Molecular Weight(MW) | 28kDa |
| Sequence | 246 amino acids |
Immunohistochemical
Immunohistochemical
Western blot
0.2-1 ug/mlPositive Control: HepG2 cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
