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Rabbit anti-GGCX polyclonal antibody - middle region

Catalog Number:OM111738
OM111738
Discount Price
OM111738-100ul
1~2 Week
100ul
OM111738-50ul
50ul
OM111738-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-GGCX polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias FLJ26629, VKCFD1
Immunogen The immunogen for anti-GGCX antibody: synthetic peptide directed towards the middle region of human GGCX
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMouseRabbitRatSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GGCX
Gene Synonyms FLJ26629
VKCFD1
Gene Full Name Gamma-glutamyl carboxylase
Gene Summary GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names FLJ26629
VKCFD1
Molecular Weight(MW) 87kDa
Sequence 758 amino acids
Database Links
Entrez Gene 2677
SwissProt ID P38435
Protein Accession NP_000812
Application

Western blot

Host: Rabbit Target Name: GGCX Sample Tissue: Hela Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GGCX Sample Tissue: HepG2 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GGCX Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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