Application
Antibody used in IHC on Human Adult Liver at 1:100.Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.Application
Antibody used in WB on Human Jurkat cells at 1 ug/ml.| Product Name | GGCX Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).1) Rieder, M.J., (2007) J. Thromb. Haemost. 5 (11), 2227-2234. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GGCX. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| GGCX antibody can be used for detection of GGCX by ELISA at 1:1562500. GGCX antibody can be used for detection of GGCX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GGCX |
|---|---|
| Alternative Names | GGCX FLJ26629 VKCFD1 |
| Molecular Weight(MW) | 87 kDa |
Application
Antibody used in IHC on Human Adult Liver at 1:100.
Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.
Application
Antibody used in WB on Human Jurkat cells at 1 ug/ml.| Application Notes | GGCX antibody can be used for detection of GGCX by ELISA at 1:1562500. GGCX antibody can be used for detection of GGCX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store GGCX antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
